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Proton Beam Therapy Resources #RTSS19

Here are some Proton resources to accompany the final day of the 4th Christie Advanced Radiotherapy Summer School.

Information on Proton Beam Therapy from NHS.UK

NICE Evidence on Proton Beam Therapy

#christieresearchers – on the Christie Research Repository

Image guidance for proton therapy

New developments in proton therapy in head and neck cancer

Dosimetric comparison of five different techniques for craniospinal irradiation across 15 European centers: analysis on behalf of the SIOP-E-BTG (radiotherapy working group)

Mathematical modelling for patient selection in proton therapy.

Clinically relevant nanodosimetric simulation of DNA damage complexity from photons and protons

Clinical intensity-modulated proton therapy for Hodgkin lymphoma: which patients benefit the most?

Proton beam therapy – the challenges of delivering high-quality evidence of clinical benefit.

Abstract ID: 171 A Monte Carlo study to reduce range uncertainty in proton beam therapy via prompt gamma-ray detection.

Practice-changing radiation therapy trials for the treatment of cancer: where are we 150 years after the birth of Marie Curie?

eBooks – Open Athens log in required

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Proton beam therapy [Dawsonera ebook]

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Proton and Charged Particle Radiotherapy [OVID ebook]

Books available at the Christie Library and Knowledge Service

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MRI from picture to proton (McRobbie et al, 2017)

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Particle radiotherapy: emerging technology for treatment of cancer (Kumar Rath & Sahoo, 2016)

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Practical radiobiology for proton therapy planning (Jones, 2017)

Follow all the action on the Summer School hashtag: #RTSS19

Speakers to follow:

@antheasaif
@marianneaznar
@normankirkby1
@finn_corinne
#WhereisHoskin — Peter Hoskin
@CatharineWest3
@RosieBHales
@achoud72
@ranmackay
@syeepei
@TheChristieSoO
@MCRCnews
@RT_physics
@RRR_UoM

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Health Information Week: Healthy Lifestyles – Stopping Smoking

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It is Health Information Week!

Each day we will be posting some bite size health information on our blog.

Monday’s theme is: Healthy Lifestyles so here are ten benefits of stopping smoking from the Live Well section of nhs.uk

1.Stopping smoking lets you breathe more easily

2.Stopping smoking gives you more energy

3.Ditch the cigarettes and feel less stressed

4.Quitting leads to better sex

5.Stopping smoking improves fertility

6.Stopping smoking improves smell and taste

7.Stop smoking for younger-looking skin

8.Ex-smokers have whiter teeth and sweeter breath

9.Quit smoking to live longer

10.A smoke-free home protects your loved ones

More information and links are on the NHS website

In case you missed it, Charlotte Finchett, lead stop smoking specialist at The Christie blogged about smoking cessationin Greater Manchester here

The Christie Library and the Cancer Information Centre both have books that may help, get in touch if you are interested.

Follow us on Twitter for more #HIW2019 content

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Novel and Specialised Radiotherapy Resources #RTSS19

The 4th Christie Advanced Radiotherapy Summer School is next week!

It promises a fantastic opportunity to learn and network, with tours of the Proton Centre and MR Linac, and a wide variety of plenary sessions workshops, debates and social events. It is not too late to register, click here to secure your spot today!

We have put together some resources around the topic of day 3 of the conference which focuses on:

Novel and Specialised Radiotherapy

Hashtags to follow: #TeamScience #radonc  #InternationalTeamScience  #cancerteamscience  #radiotherapy #TeamScience #Theragnostics

Summer School Hashtag: #RTSS19

Speakers to follow:

@antheasaif
@marianneaznar
@normankirkby1
@finn_corinne
#WhereisHoskin — Peter Hoskin
@CatharineWest3
@RosieBHales
@achoud72
@ranmackay
@syeepei
@TheChristieSoO
@MCRCnews
@RT_physics
@RRR_UoM

RESOURCES from #ChristieResearchers

Clinical trials targeting hypoxia.

Tharmalingham, Hannah; Hoskin, Peter 2018, Br J Radiol

An accurate method to quantify breathing-induced prostate motion for patients implanted with electromagnetic transponders.

Giandini, T; Panaino, Costanza M V; Avuzzi, B; Morlino, S; Villa, S; Bedini, N; Carabelli, G; Frasca, S; Romanyukha, A; Rosenfeld, A; Pignoli, E; Valdagni, R; Carrara, M 2017, Tumori

Results from a clinical trial evaluating the efficacy of real-time body surface visual feedback in reducing patient motion during lung cancer radiotherapy.

Price, Gareth J; Faivre-Finn, Corinne; Stratford, Julia; Chauhan, Sheena; Bewley, Michelle; Clarke, Laura; Johnson, Corinne; Moore, Christopher J; 2017:1-8 Acta Oncol

R-IDEAL: a framework for systematic clinical evaluation of technical innovations in radiation oncology.

Verkooijen, H; Kerkmeijer, L; Fuller, C; Huddart, R; Faivre-Finn, Corinne; Verheij, M; Mook, S; Sahgal, A; Hall, E; Schultz, C 2017, 7:59 Front Oncol

Absolute calibration of the elekta unity MR Linac using the UK code of practice for high-energy photon dosimetry.

Budgell, Geoff J; Gohil, Pooja; Agnew, James Paul; Berresford, Joe; Billas, I; Duane, S World Congress on Medical Physics and Biomedical Engineering 2018. IFMBE Proceedings. 3. Prague, Czech Republic: Springer; 2019. p. 455-8.

 

Open Access Resources from #ChristieResearchers

 

Improving molecular radiotherapy dosimetry using anthropomorphic calibration

Price, E; Robinson, P; Cullen, M; Tipping, Jill; Calvert, Nicholas; Hamilton, David; Oldfield, C; Page, Emma; Pietras, B; Smith, A Phys Med. 2019 Feb;58:40-6.
In silico non-homologous end joining following ion induced DNA double strand breaks predicts that repair fidelity depends on break density.

Henthorn, N; Warmenhoven, J; Sotiropoulos, M; Mackay, Ranald I; Kirkby, Norman; Kirkby, Karen J; Merchant, Michael J; 2018, 8(1):2654 Sci Rep

 

Mechanistic modelling supports entwined rather than exclusively competitive DNA double-strand break repair pathway

Ingram, S; Warmenhoven, J; Henthorn, Nicholas; Smith, E; Chadwick, A; Burnet, Neil G; Mackay, Ranald I; Kirkby, Norman; Kirkby, Karen J; Merchant, Michael J; Sci Rep. 2019; 9(1):6359.

 

Meetings and Proceedings

Locally advanced lung cancer radiotherapy in deep inspiration breath hold: dosimetric benefits from a prospective trial

Josipovic, M; Aznar, Marianne Camille; Rydhog, J; Thomsen, J; Damkjaer, S; Nygard, L; Pohl, M; Langer, S; Specht, L; Persson, G  J Thorac Oncol. 2018 Oct;13(10):S372-S373.

 

Motion of the uterine tip during radiotherapy for cervical cancer is not correlated with survival.

Cree, Anthea; Morrison, S; Price, Gareth J; van Herk, Marcel; McWilliam, Alan; Choudhury, Ananya; 2018, 127:S821-S821 Radiother Oncol

 

Small residual setup errors after image-guided radiotherapy affect heart dose and are linked to overall survival

Johnson, Corinne; Price, Gareth J; McWilliam, Alan; Faivre-Finn, Corinne; van Herk, Marcel; J Thorac Oncol. 2018;13(10):S439-S40.

 

REQUITE big data resource for validating predictive models and biomarkers of radiotherapy toxicity.

West, Catharine M L; Elliott, Rebecca M; Talbot, C; Webb, A; Seibold, P; Azria, D; De Ruysscher, D; Symonds, R; Veldeman, L; Rosenstein, B; Lambin, P; Burr, T; Enriquez, S; Rancati, T; Vega, A; Chang-Claude, J 2018, 127: S78 Radiother Oncol

 

Feasibility of Mobius 3D as an independent MU checker for the adaptive work flow on the MR-Linac

Pollitt, Andrew; Budgell, Geoff J; Pooler, Alistair; Wood, Joe; Chuter, Robert; McWilliam, Alan 2018, 127:S1191-S1192 Radiother Oncol

 

Understanding the mechanisms of adding immunoregulatory agents together with radiotherapy.

Illidge, Timothy M 2018, 127: s5-s5 Radiother Oncol

 

EBooks – OpenAthens required

9789811066580

Basics of planning and management of patients during radiation therapy a guide for students and practitioners [DawsonEra ebook] Mukherji, Ashutosh 2018

Healthcare and big data management [Dawsonera ebook] Bairong, Shen 2017

Books in the Christie Library

Basic clinical radiobiology — Joiner, Michael C and Van Der Kogel, Albert
BS/Joi 2018

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Radiobiology for the radiologist — Hall, Eric J and Giaccia, Amato J
BS/Hal 2018

Radiation biology for medical physicists — Sureka, C S and Armpilia, C
BS/Sur 2017

Radiotherapy in practice: imaging — Hoskin, Peter; Goh, Vicky
GM.RN/Hos 2010

Radiotherapy in practice: radioisotope therapy — Hoskin, Peter
GM.RN/Hos 2007

EJOURNALS

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British journal of radiology– BARP Section [BIR Archive]
— Fulltext: 1924 – present available at The Christie Library and Knowledge Service

There is still time to secure your place at the Summer School, the full programme and tickets are available here.

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Recent nursing journal articles on women’s cancer

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The British Journal of Nursing is a useful resource for all nursing staff.  Here are 2 recent articles that would be of interest to those working with breast cancer patients

 

BJHA

Here are some useful links for Healthcare assistants and their supervisors.  All articles need an OpenAthens login.  Christie staff can self-register here

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Cervical cancer screening: How can we increase uptake? (Available with OpenAthens)
Published Online: 31 Jan 2019

Breast surgery for metastatic breast cancer
Published Online: 4 Jul 2018

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Adaptive Radiotherapy Resources

Ahead of the forthcoming 4th Annual Christie Advanced Radiotherapy Summer School in July, we will be producing a series of blog posts with recommended resources.

Day two of the Summer School is all about Adaptive Radiotherapy, @TheChristieSoO and other attendees will be tweeting from the conference using #RTSS19

Here are some people and hashtags you might like to check out on twitter:

@finn_corinne
#WhereisHoskin — (Prof Peter Hoskin
@CatharineWest3
@antheasaif
@RosieBHales
@achoud72
@syeepei 
@MCRCnews
@RT_physics
@RRR_UoM

#RTSS19
#christieresearchers
#TeamScience
#radonc
#InternationalTeamScience
#cancerteamscience
#MRLinac
#radiotherapy
#TeamScience
#ProstateCancer
#brachytherapy

Recent resources from #christieresearchers:

Journals for Twitter

Magnetic resonance imaging-guided adaptive radiation therapy: A ‘game changer’ for prostate treatment?
OPEN ACCESS

The potential value of MRI in external-beam radiotherapy for cervical cancer.

Real-time adaptive planning method for radiotherapy treatment delivery for prostate cancer patients, based on a library of plans accounting for possible anatomy configuration changes

Systematic review:
MRI-guided prostate adaptive radiotherapy – A systematic review.

Real-time adaptive planning method for radiotherapy treatment delivery for prostate cancer patients, based on a library of plans accounting for possible anatomy configuration changes  

External beam (EBRT) and HDR brachytherapy (BT) in prostate cancer: impact of EBRT volume.
OPEN ACCESS

Meetings and Proceedings

External beam (EBRT) and HDR brachytherapy (BT) in prostate cancer: impact of EBRT volume.
OPEN ACCESS

EBooks

Sectional anatomy by MRI and CT [ClinicalKey ebook] — Anderson, Mark W; Fox, Michael G – 4th ed 2016

Fundamentals of Body MRI — Roth, Christopher G – 2nd ed 2017

Brachytherapy [ovid ebook] — Devlin, Phillip M; Cormack, Robert A – 2nd ed 2016

Books available in the library

9781498708548

Human sectional anatomy pocket atlas of body sections, CT and MRI images.

Ellis, Harold; Logan, Bari M et al. (2017) 4th ed

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MRI in practice.

Westbrook, Catherine. (2018) 5th ed

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Hoskin, Peter; Coyle, Catherine (2013) 2nd ed

EJOURNALS

Brachytherapy [ClinicalKey eJournal]
Journal of Contemporary Brachytherapy [EBSCO ejournal]

Other resources:

MR-Linac at The Christie Blog

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Stereotactic Ablative Radiotherapy (SABR) Resources

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Ahead of the forthcoming 4th Annual Christie Advanced Radiotherapy Summer School in July, we will be producing a series of blog posts with recommended resources.

Day one of the Summer School is all about SABR: Stereotactic Ablative Radiotherapy.

“SABR uses small, thin beams of radiation directed from different angles that meet at the tumour. This means the tumour gets a high dose of radiation, while the surrounding healthy tissues gets a low dose. This lowers the risk of damaging the healthy normal cells surrounding the tumour.”

(Macmillan, 2019)

RESOURCES from #christieresearchers:

BJR van Herk 2019

The advanced radiotherapy network (ART-NET) UK lung stereotactic ablative radiotherapy survey: national provision and a focus on image guidance – Brown, Sean; Faivre-Finn, Corinne; van Herk, Marcel – BJR 2019

The potential value of MRI in external-beam radiotherapy for cervical cancer – – Cree, Anthea; Livsey, Jacqueline E; Barraclough, Lisa H; Dubec, Michael; Hambrock, Thomas; van Herk, Marcel; Choudhury, Ananya; McWilliam, Alan – Clin Oncol 2018

Isotoxic intensity modulated radiotherapy (IMRT) in stage III non-small cell lung cancer (NSCLC) – a feasibility study

Open Access:

BMJ Open Faivre Finn 2018

Study protocol for the SARON trial: a multicentre, randomised controlled phase III trial comparing the addition of stereotactic ablative radiotherapy and radical radiotherapy with standard chemotherapy alone for oligometastatic non-small cell lung cancer. – – Faivre-Finn, Corinne – BMJ Open 2018 – Open Access

Articles

ESTRO ACROP consensus guideline on implementation and practice of stereotactic body radiotherapy for peripherally located early stage non-small cell lung cancer.

Meetings and Proceedings

An audit of adaptive radiotherapy in a large centre — Chuter, Robert; Brown, Sean; Whitehurst, Philip: Handley, Julia; Faivre-Finn, Corinne; van Herk, Marcel;

EBooks

FAO Christie Staff: links will take you straight to the content after you log on with Open Athens

Basics of planning and management of patients during radiation therapy a guide for students and practitioners [DawsonEra ebook] – Mukherji, Ashutosh – 1e 2018

Brain metastases from primary tumors, Vol lll [ClinicalKey ebook] – Hayat, M 1e 2016

Principles of neurological surgery [ClinicalKey ebook] – Ellenbogen, Richard – 4th ed 2018

Stereotactic Body Radiation Therapy [OVID ebook] – eBook – Kavanagh, Brian D Timmerman, Robert D – 2005

Books available in the Christie Library

9780340972939
Clinical oncology – basic principles and practice – Neal, Anthony J and Hoskin, Peter J – 4th ed 2009

9780340927731

Practical radiotherapy planning – Barrett, Ann; Dobbs, Jane et al – 4th ed 2009

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Radiation Oncology Management Decisions Chao, K S Clifford; Perez, Carlos A et al

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Radiotherapy in practice: brachytherapy – Hoskin, Peter and Coyle Catherine – 2nd ed 2013

9780199696567

Radiotherapy in practice: external beam therapy – Hoskin, Peter – 2nd ed 2012

 

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Stereotactic body radiotherapy – Gaya, Andrew and Mahadevan, Anand – 2013

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EJOURNALS

British journal of radiology– BARP Section [BIR Archive]  Fulltext: 1924 – present

International Journal of Radiation Oncology, Biology, Physics [ClinicalKey eJournal]  Fulltext: 2007- present

MAGMA: Magnetic Resonance Materials in Physics, Biology & Medicine [EBSCO ejournal] Fulltext: 2011 – Present (12 month embargo)

Radiotherapy and Oncology [ClinicalKey eJournal] – Fulltext: 2007- present

Medical Dosimetry [ClinicalKey eJournal] – Fulltext: 2007- present

Resources for your patients

Cancer Research UK guide to Stereotactic Radiotherapy

Christie Patient Booklets

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For more information on the programme, and to secure your spot for the summer school, click here

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Researchers: set up your ORCID profile today!

orcid02.pngWhat is ORCID?

ORCID (Open Researcher and Contributor ID) is a 16-digit unique identifier that helps to disambiguate researchers from people with the same, or similar, names. It looks a bit like this: 0000-0000-0000-0000.

This identifier helps systems (e.g. publisher submission systems and grant application systems) talk to each other and ensures that researchers are accurately connected to and credited for their work.

ORCID therefore improves recognition and discoverability of your research!

 

What is ORCID? from ORCID on Vimeo.

ORCID also gives researchers a public-facing profile that they can keep updated without requiring lots of manual data entry.

Researchers can set up connections with indexes like PubMed, CrossRef and Scopus so that information about publications can be automatically added to their profiles.

It only takes a couple of minutes to create an ORCID. Just go to orcid.org and click “Register now”. For help setting yours up please do not hesitate to contact the library: library@christie.nhs.uk

Need more convincing? ORCID has some great reasons why:

Why ORCID? from ORCID on Vimeo.

Thanks to Stephen Carlton, Research Services Librarian at The University of Manchester for his assistance with this blog post.

For any enquiries about setting up an ORCID, contact us: library@christie.nhs.uk

 

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It’s back – The Christie Randomised Coffee Trial (RCT)

The idea behind RCTs is to get people talking to each other again. Participants register to take part and are paired up at random with someone else in the organisation to have an informal conversation. Participants meet and have a chat for about 15 minutes or so. RCTs help us connect with our colleagues, learn from, and about each other, and help break down silos. It’s easy and informal!

When is it?

We are planning to run it from Monday 13 May to Sunday 19 May 2019 to coincide with Mental Health Awareness Week, although meetings don’t have to take part in that week

How do I sign up?

email: library@christie.nhs.uk before the 1 May 2019 giving your job title and location and name if not included in your email address

What happens then?

  1. We will pair you at random with someone else at The Christie. It could literally be anyone from a clinical colleague to a volunteer to the Chief Executive., depending on who signs up.
  2. We will email you before 3rd May to introduce you to your RCT partner.
  3. It is then up to the two of you to get in touch with each other and organise a 15-30 minute chat over coffee (sorry you will have to provide your own drink).
  4. It would be nice if you can meet up during mental health week (13th-19th May) but it is not essential.
  5. It need not be coffee – it can be any drink or refreshment, whatever works best for you.
  6. If the two of you are on different sites, you can have a virtual RCT, say over Skype or the phone, still with a cup of coffee.
  7. After the RCT, we will send you another email asking how you found the experience.

Comments from our last RCTs in May 2018 & Oct 2018

This worked well. Good to connect with colleagues for personal well-being, as well as learning about other aspects of the Trust and broadening our network to help us work effectively in our roles.

Great insight into what someone else in the hospital does, even though we had very different roles we had a few people/projects in common. We also found we had other random things in common which was a funny highlight. We are from quite different generations and we’re by no means best buddies but I think if we saw each other around the hospital we’d say hi, we’ve not had contact since but it was still a positive experience.

I learnt about her role in a different team than I work in and I thought my partner was a fascinating and inspirational woman

Very good idea in addressing loneliness/individualistic culture. I introduced the idea within my workplace but it was very close to the deadline. I think repeating the event regularly would encourage more people to get involved

I found the meeting to be very interesting as it allowed me to discuss how I felt within my Job with my partner. We both spoke in depth about our journey’s so far at the Christie and our plans for further/future development within our respective roles.

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New Resource: JCO Precision Oncology Journal

C7NAbLyWwAEC9w7JCO Precision Oncology is one of our new resources for 2019 so we felt we should introduce it properly to staff at The Christie.

JCO Precision Oncology covers the science and practice of precision oncology and define genomics- and other biomarker-driven clinical care of patients with cancer.

This includes actionable cancer genomics, personalized translational and clinical oncology research, and recent treatment advances based on tumor molecular profiling.

JCO Precision Oncology is:

Peer-reviewed

online-only

article-based 

JCO Precision Oncology publishes: 

original research (including basket trials, exceptional response results, informatics, computational approaches, mechanism and evidence-based case reports and small series of educational value)

reports

opinions (from extensive expert driven commentary to editorials)

reviews

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Access JCO Precision Oncology via Browzine – remember to log into your OpenAthens

Contact the library with any queries library@christie.nhs.uk

 

 

 

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Christie Library Spring Newsletter

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Greetings from the Library Team, isn’t it starting to feel like Spring?

In that case, it is time for an update on some of the recent library happenings.

  • Nurse Prescribing has changed it’s name to Journal of Prescribing Practice.
  • A reminder that a new journal for 2019 is JCO: Precision Medicine – you can browse the articles here via Browzine – You have access to many hundreds of journals. Do ask us if you can’t find what you need, sometimes you just need to look in a different place and we are here to troubleshoot for you.
  • We have bought dozens of new book titles – many of which we have tweeted about, but please do come and have a browse or drop us an email if you are need of something.
  • There will be a few changes to the databases you can use to do literature searching in HDAS from 1st April. Health Business Elite (HBE) will no longer be available. Ovid Emcare will added, which is a nursing and allied health database ideal for practice, research, or education.
  • In conjunction with the recent Health and Wellbeing event, Mary is organising another Randomised Coffee Trial, email library@christie.nhs.uk to be matched up with someone random in the Trust, and go for a coffee! This is a great opportunity to meet someone you may never encounter in your day to day role, and find out more about what goes on in the hospital.
  • Our book group has now met twice, the next meeting is on 2nd May 2019, details below.

Reading Group

Recent blog posts you may have missed:

Nursing Journals available now online

Mental Health Resources

Metastatic Spinal Cord Compression (MSCC) Resources

Introductory Haematology Resources

Contouring Resources: Oncology imaging for Clinical Oncologists and Fellows

Ebooks for Christie nurses