Long COVID

MEDBOX issue brief on Long COVID

The MEDBOX team publishes issue briefs on different topics around COVID-19. They have prepared a new issue brief on the long-term effects of coronavirus infection, Long COVID (also known as long-haul COVID, post-acute COVID-19, long-term effects of COVID, or chronic COVID). The issue brief includes many links to relevant reports and guidance about long COVID.

Read the brief here

World Health Organization (WHO) Report

Global status report on the public health response to dementia

This report finds that only a quarter of countries worldwide have a national policy, strategy or plan for supporting people with dementia and their families. Half of these countries are in WHO’s European Region, with the remainder split between the other regions. Yet even in Europe, many plans are expiring or have already expired, indicating a need for renewed commitment from governments. At the same time, the number of people living with dementia is growing according to the report: WHO estimates that more than 55 million people (8.1 per cent of women and 5.4 per cent of men over 65 years) are living with dementia. This number is estimated to rise to 78 million by 2030 and to 139 million by 2050.

Report from the Nuffield Trust

Untapped? Understanding the mental health clinical support workforce

This report explores the roles, responsibilities and diversity of mental health clinical support staff. It aims to draw out the number and distribution of this workforce and issues around recruitment, career progression and retention.

Covid 19

Current awareness updates

Covid-19 Loneliness Fund evaluation.
Department for Digital, Culture, Media and Sport; 2021.
[The Covid-19 Loneliness Fund was launched in May 2020 to support 9 national organisations working to tackle loneliness and build social connections to help them to continue and adapt their critical work during the pandemic. The National Centre for Social Research was appointed as evaluator for this fund. This report presents the results of a process evaluation of the fund, to see how it supported the delivery and adaption of services aimed at addressing loneliness during Covid-19 restrictions.]

Annual Organ Donation and Transplantation Data for Black, Asian, and Minority Ethnic (BAME) communities: report for 2020/2021.
NHS Blood and Transplant; 2021.
[This report provides information related to organ donation and transplantation within the white and Black, Asian and minority ethnic (BAME) communities in the UK. It finds the Covid-19 pandemic has had a significant impact on the numbers of living donor kidney transplants that could be performed. In 2020/21 there was a comparable drop in both white and non-white deceased donors, but a 61 per cent decrease in the number of BAME living donors, compared with a 58 per cent drop overall.]

Association of the COVID-19 lockdown with smoking, drinking and attempts to quit in England: an analysis of 2019–20 data.
Addiction; 2021.
[Following the March 2020 COVID-19 lockdown, smokers and high-risk drinkers in England were more likely than before lockdown to report trying to quit smoking or reduce alcohol consumption and rates of smoking cessation and use of remote cessation support were higher. However, high-risk drinking prevalence increased post-lockdown and use of evidence-based support for alcohol reduction by high-risk drinkers decreased with no compensatory increase in use of remote support.]

Public Health

Current awareness updates

Alcohol and self-harm: A qualitative study.
Alcohol Change UK; 2021.
[This study explores how and why alcohol and self-harm are related, and how alcohol, self-harm, and related services, are experienced and understood. Eleven people who had experience with self-harm and alcohol use were recruited through mental health support organisations across England and Wales. Interviews invited participants to ‘tell their stories’ about self-harm, alcohol use, the relationship between the two practices and their experiences with services in relation to these.]

Chronic kidney disease: assessment and management.
National Institute for Health and Care Excellence (NICE); 2021.
[This guideline covers care and treatment for people with, or at risk of, chronic kidney disease (CKD). It aims to prevent or delay the progression, and reduce the risk of complications and cardiovascular disease. It also covers managing anaemia and hyperphosphataemia associated with chronic kidney disease.]

Bonded By Blood: A Mothers Story.
ACLT; 2021.
[A new nationwide blood donation campaign, created by a group of Black health charities and community organisations with support from NHS Blood and Transplant, the campaign will focus on amplifying the need for more blood donors of Black heritage to donate. It is launched in memory of sickle cell patient Richard Okorogheye. The campaign will share the stories of mothers with children who receive regular blood transfusions.]

Good Childhood Report 2021.
The Children’s Society; 2021.
[Our Good Childhood Report 2021 shows that modern life continues to erode the happiness of young people. Dissatisfied with school, friendships and how they look, children deserve drastic change. Our tenth annual report finds that 7% of 10 to 15 year-olds (an estimated 306,000 children) in the UK are not happy with their lives.]

The health impacts of Sure Start.
Institute for Fiscal Studies (IFS); 2021.
[This briefing note from the Institute for Fiscal Studies extends the evidence from its previous 2019 report to show how Sure Start has influenced children’s health. Specifically it assesses the programme’s impact on hospitalisations of very young children, who are still eligible to use its services (ages 1-4), and of adolescents (ages 12-15), who may still enjoy medium-term benefits from Sure Start exposure.]

Building Connections Fund evaluation final reports.
Department for Digital, Culture, Media and Sport; 2021.
[The £11.5 million Building Connections Fund (BCF) was the first ever government fund dedicated to tackling loneliness in England. There are two separate reports for this evaluation: part one, the evaluation report, which covers findings before the Covid-19 pandemic; and part two, focusing on the evaluation activity following the Covid-19 pandemic.]

Public Health

Current awareness updates

Drug users urged to be extra careful following a high number of likely heroin overdoses.
Public Health England (PHE); 2021.
[Public Health England (PHE) has issued a warning of a sharp rise in the number of overdoses linked to people using drugs in several areas across England. To date, there have been at least 46 poisonings resulting in 16 deaths but investigations are still ongoing. The areas affected include South London, the South East, South West and East of England.]

Mental Health Crisis Care Profile.
PHE Fingertips; 2021.
[The Crisis Care Profile collates and analyses a wide range of publicly available data on associated prevalence of mental health crisis. Risk factors include access to care, treatment, and outcomes. Includes risk factors around age, deprivation, illness and disabilities, crime and social isolation. Other topics – urgent and emergency care, quality of treatment, access to support. Data available by local authorities.]

Dental health: migrant health guide.
Public Health England (PHE); 2021.
[Advice and guidance on the health needs of migrant patients for healthcare practitioners. 17 August 2021: New model of care to support refugees and asylum seekers to access NHS dental services.]

Cervical screening: support for people who find it hard to attend.
Public Health England (PHE); 2021.
[Guidance on support for people who find it hard to attend cervical screening due to having a mental health condition, or having experienced trauma or abuse. 16 August 2021: Clarification that this guidance is based on research conducted with users of mental health services and addition of signposting to guidance to support other underserved groups.]

Oral healthcare: model for asylum seekers and refugees.
Public Health England (PHE); 2021.
[This model of care provides professionals with guidance to support access to NHS dentists. Asylum seekers and refugees can face barriers when accessing NHS dentists. This model of care details the processes, rights and entitlements to care and includes supporting information and links to forms and guidance. It is designed for local authorities, support services and health professionals who work with asylum seekers and refugees.]

Antenatal care.
National Institute for Health and Care Excellence (NICE); 2021.
[This quality standard covers care for healthy women and their babies during pregnancy (up to 42 weeks). It covers routine antenatal care in primary, community and hospital settings. It describes high-quality care in priority areas for improvement. In August 2021, changes were made to align this quality standard with the updated NICE guideline on antenatal care.]


Service specification: Cystinosis diagnosis and co-ordination of management (all ages).
NHS England; 2021.
[This service specification covers the provision of services for patients with Cystinosis, all ages.]

Continuous positive airway pressure for the treatment of obstructive sleep apnoea/hypopnoea syndrome.
National Institute for Health and Care Excellence (NICE); 2021.
[Evidence-based recommendations on continuous positive airway pressure for treating obstructive sleep apnoea/hypopnoea syndrome in adults. August 2021: The recommendation on continuous positive airway pressure (CPAP) for mild obstructive sleep apnoea/hypopnoea syndrome (OSAHS) has been updated and replaced by recommendation 1.5.2 on CPAP for mild OSAHS in the NICE guideline on obstructive sleep apnoea/hypopnoea syndrome and obesity hypoventilation syndrome in over 16s.]

Obstructive sleep apnoea/hypopnoea syndrome and obesity hypoventilation syndrome in over 16s.
National Institute for Health and Care Excellence (NICE); 2021.
[This guideline covers the diagnosis and management of obstructive sleep apnoea/hypopnoea syndrome (OSAHS), obesity hypoventilation syndrome (OHS) and chronic obstructive pulmonary disease with OSAHS (COPD–OSAHS overlap syndrome) in people over 16. It aims to improve recognition, investigation and treatment of these related conditions.]

Ethnic differences in SARS-CoV-2 vaccine hesitancy in United Kingdom healthcare workers: Results from the UK-REACH prospective nationwide cohort study.
Woolf K. The Lancet Regional Health – Europe 2021;8(-):100180.
[Using a nationwide prospective cohort study and qualitative study in a multi-ethnic cohort of clinical and non-clinical UK healthcare workers (HCWs) researchers analysed ethnic differences in SARS-CoV-2 vaccine hesitancy. Of the 11,584 HCWs included in the cohort analysis, 23% (2704) reported vaccine hesitancy. Ethnicity was a significant predictor of hesitancy.]

Association of the COVID-19 lockdown with smoking, drinking and attempts to quit in England: an analysis of 2019–20 data.
Addiction; 2021.
[Following the March 2020 COVID-19 lockdown, smokers and high-risk drinkers in England were more likely than before lockdown to report trying to quit smoking or reduce alcohol consumption and rates of smoking cessation and use of remote cessation support were higher. However, high-risk drinking prevalence increased post-lockdown and use of evidence-based support for alcohol reduction by high-risk drinkers decreased with no compensatory increase in use of remote support.

Everybody active, every day: 5 years on.
Public Health England (PHE); 2021.
[Summary of the 5 year review to the national physical activity framework, ‘Everybody active, every day’ and the PHE response.]

Quality in Qual: a proposed framework to commission, judge and generate good qualitative evaluation in wellbeing impacts.
whatworkswellbeing; 2021.
[Based on interviews with ten leading organisations and individuals who have in-depth evaluation and methodological expertise this report sets out why work on qualitative evaluation is valuable and important, what resources already exist. The report identifies six prompts for potential uses of qualitative research in evaluations.]

Genomics nation: A benchmark of the size and strengths of the UK genomics sector.
UK Bioindustry Association; 2021.
[The NHS Long Term Plan promised greater focus on prevention to help people stay healthy and ease the burden on the health service. The early detection of disease, rather than merely the diagnosis and treatment of illness, will be critical to achieve this objective. The NHS Genomic Medicine Service (GMS), launched in 2018, provides a single, national coordinated approach to genomic testing and genomic research in the NHS.]

A joint thematic inspection of community-based drug treatment and recovery work with people on probation.
HM Inspectorate of Probation (HMIP); 2021.
[Probation services across England and Wales supervise nearly 156,000 people in the community. HM Inspectorate of Probation estimates that almost 75,000 of these individuals have a drugs problem, yet fewer than 3,000 people were referred by probation services to specialist drug misuse treatment in 2019/2020. HMIP partnered with the Care Quality Commission to examine how probation services supervise this cohort and found probation services are responding poorly to drugs misuse and addiction cases.]

Covid 19

Current awareness updates

COVID-19 rapid guideline: managing COVID-19.
National Institute for Health and Care Excellence (NICE); 2021.
[On 10 August 2021, NICE corrected an error in the practical info section of the recommendations on corticosteroids. The dose of prednisolone for children with a greater than 44-week corrected gestational age is 1 mg/kg.]

Impact of Covid-19 on physical activity in children in the UK.
Carried out by Frankie Marcelline from Brighton and Sussex on 9/8/2021
[This evidence search consists of short reports on the impact of Covid-19 on physical activity in children in the UK. Most of the results are summaries from Sport England which works to encourage all age groups in the uptake of sports and physical activities in England.]

The impact of Covid-19 to date on older people’s mental and physical health: one year on.
Age UK; 2021.
[This report finds that the impact of the pandemic on the health and wellbeing of some older people in early 2021 is so demonstrably severe that it raises big questions over whether they will be able to ‘bounce back’. The adverse effect may prove long lasting in many cases, or even irreversible, with big implications for the NHS and social care in the months and years to come.]


Public Health

Current awareness updates

Opioid substitution treatment: service self-assessment tool.
Public Health England (PHE); 2021.
[Self-assessment tool, good-practice examples and resources for community drug treatment services to help them deliver OST in line with clinical guidance.]

Opioid substitution treatment: guide for keyworkers.
Public Health England (PHE); 2021.
[This guide provides drug treatment and recovery workers with the information they need to deliver good quality opioid substitution treatment (OST) to service users. It will also help them have more effective conversations about OST with service users and the local multidisciplinary team, including prescribers.]

Diagnostic test accuracy of telehealth assessment for dementia and mild cognitive impairment. [Abstract]
McCleery J. Cochrane Database of Systematic Reviews 2021;7:CD013786.
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[OBJECTIVES: Primary objective: to assess the diagnostic accuracy of telehealth assessment for dementia and mild cognitive impairment. Secondary objectives: to identify the quality and quantity of the relevant research evidence; to identify sources of heterogeneity in the test accuracy data; to identify and synthesise any data on patient or clinician satisfaction, resource use, costs or feasibility of the telehealth assessment models in the included studies.]

A systematic review and meta-analysis of school-based interventions with health education to reduce body mass index in adolescents aged 10 to 19 years.
Jacob CM. The International Journal of Behavioral Nutrition and Physical Activity 2021;18(1):doi: 10.1186/s12966-020-01065-9.
[CONCLUSIONS: Findings from our review suggest that school-based health education interventions have the public health potential to lower BMI towards a healthier range in adolescents. Multi-component interventions involving key stakeholders such as teachers and parents and digital components are a promising strategy.]

Inter-individual differences in body mass index were not observed as a result of aerobic exercise in children and adolescents with overweight and obesity.
Kelley GA. Pediatric Obesity 2021;16(1):e12692.
[Exercise has been recommended as an important intervention for reducing adiposity in children and adolescents with overweight and obesity. However, inter-individual differences for BMI in kg/m2 were not observed as a result of aerobic exercise in children and adolescents with overweight and obesity.]

Drowning prevention and awareness.
World Health Organization (WHO); 2021.
[Resources relating to drowning awareness and prevention can be found at the end of this WHO report.]

Covid 19

Current awareness updates

Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study.
Drake TM. The Lancet 2021;:https://doi.org/10.1016/S0140-6736(21)00799-6.
[Complications and worse functional outcomes in patients admitted to hospital with COVID-19 are high, even in young, previously healthy individuals. Acute complications are associated with reduced ability to self-care at discharge, with neurological complications being associated with the worst functional outcomes. COVID-19 complications are likely to cause a substantial strain on health and social care in the coming years.]

COVID-19 and the digital divide: Supporting digital inclusion and skills during the pandemic and beyond.
Centre for Ageing Better; 2021.
[This report offers examples of good practice and recommendations for organisations that deliver services to users and help digitally excluded people with skills training. The report finds that the key to building digital inclusion isn’t only about getting more people online, but also building skills and confidence.]

Alcohol consumption and harm during the COVID-19 pandemic.
Public Health England (PHE); 2021.
[A report collating data on alcohol consumption and alcohol-related harm in England during the COVID-19 pandemic and comparing it to data from previous years. The report improves our understanding of how alcohol consumption and harm changed in England while physical and social restrictions to prevent and control coronavirus were in place. The findings help to understand whether pandemic-related changes have affected rates of alcohol hospital admissions and deaths as well as health inequalities.]

COVID-19 vaccination of children and young people aged 12 to 17 years: JCVI statement.
Department of Health and Social Care (DHSC); 2021.
[Statement from the Joint Committee on Vaccination and Immunisation (JCVI) on COVID-19 vaccination of children and young people aged 12 to 17 years.]

NHS COVID Pass Verifier app.
NHS England; 2021.
[A fast, secure and easy way of allowing people to demonstrate their COVID pass is valid, giving staff confidence in the legitimacy of what is being presented to them. It is a fast, secure way to scan the 2D barcode on an individual’s NHS COVID Pass and verify whether or not they have been fully vaccinated against COVID-19, had a negative test, or have recovered from the virus – allowing staff to check the legitimacy of what is being presented to them.]

JCVI issues advice on COVID-19 vaccination of children and young people.
Public Health England (PHE); 2021.
[The Joint Committee on Vaccination and Immunisation (JCVI) is today advising that children at increased risk of serious coronavirus (COVID-19) disease are offered a vaccine.]

The impact of Brexit and COVID-19 on nursing in the UK. [Comment]
Carvalho F. British Journal of Nursing 2021;30(13):822-823.
[Over the years, many experts have stated that nursing in the UK is in crisis and nurses are struggling owing to the increasing number of older and sicker patients, staff shortages and budget cuts that have affected working conditions (Beech et al, 2019). With the rise of the COVID-19 pandemic, unprecedented levels of pressure were placed on an already strained nursing workforce.]

A healthy recovery – Acting on findings from the COVID-19 impact inquiry
The Health Foundation; 2021.
[Launched in October 2020, the COVID-19 impact inquiry has been carefully exploring the pandemic’s broad impact on health and what this means for improving health and reducing health inequalities in the UK – now and in the future. The inquiry launched its final report on 6 July 2021. This webinar, held on the same day, discussed key issues raised in the report – the impact of the pandemic and what needs to be done in recovery to create a healthier, fairer society.]

Unequal pandemic, fairer recovery: The COVID-19 impact inquiry report.
The Health Foundation; 2021.
[By mid-March 2021 the pandemic had led to 119,000 excess deaths in the UK and in 2020 caused a 9.9% drop in GDP. Behind these overall figures lie the unequal burdens carried by different population groups and regions. Although the pandemic is still ongoing, this report explores these impacts and the range of different, intersecting factors influencing them. It provides an initial assessment of the effects of the pandemic using evidence available up to May 2021.]