Brain, awz099, https://doi.org/10.1093/brain/awz099
This study describes a recently recognized disease entity, limbic-predominant age-related TDP-43 encephalopathy (LATE). LATE shares similar symptoms to Alzheimer’s disease, but it is a distinct disease linked to different brain proteins. Interventions designed for Alzheimer’s disease will therefore be ineffective for LATE. Developing an understanding of LATE will hopefully lead to new avenues of research into dementia treatments and care.
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