Transapical transcatheter mitral valve-in-valve implantation for a failed surgically implanted mitral valve bioprosthesis – NICE interventional procedure guidance [IPG541]

The National Institute for Health and Care Excellence (NICE) has issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on transapical transcatheter mitral valve-in-valve implantation for a failed surgically implanted mitral valve bioprosthesis in December 2015. Coding

Trastuzumab emtansine for treating HER2-positive, unresectable locally advanced or metastatic breast cancer after treatment with trastuzumab and a taxane – NICE technology appraisal guidance [TA371]

Trastuzumab emtansine (Kadcyla) is not recommended. This drug is for adults with advanced HER2-positive breast cancer that has been treated before with trastuzumab and a taxane (paclitaxel or docetaxel). Related NICE Pathway Advanced breast cancer

Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis – NICE technology appraisal guidance [TA373]

Abatacept (Orencia), adalimumab (Humira), etanercept (Enbrel) and tocilizumab (RoActemra) are recommended as possible treatments for people with polyarticular juvenile idiopathic arthritis. Adalimumab and etanercept are recommended as possible treatments for people with enthesitis-related juvenile idiopathic arthritis. Etanercept is recommended as

Erlotinib and gefitinib for treating non-small-cell lung cancer that has progressed after prior chemotherapy – NICE technology appraisal guidance [TA374]

Erlotinib (Tarceva) is recommended as a possible treatment for people with locally advanced or metastatic non‑small‑cell lung cancer that has already been treated with non-targeted chemotherapy because of delayed confirmation of epidermal growth factor receptor tyrosine kinase (EGFR‑TK) mutation status,

The use of measures of obesity in childhood for predicting obesity and the development of obesity-related diseases in adulthood: a systematic review and meta-analysis – Health Technology Assessment Volume: 19 Issue: 43

It is uncertain which simple measures of childhood obesity are best for predicting future obesity-related health problems and the persistence of obesity into adolescence and adulthood. This study aims to investigate the ability of simple measures, such as body mass index