Category: Immunology

Preeclampsia: Basic, Genomic, and Clinical

Posted onAuthorKieran Lamb

Pages: 286 Size: 4.35 MB Format: PDF Publisher: Springer Singapore
Published: 01 January, 2018
eISBN-13: 9789811058912

This volume is an excellent guide that comprehensively illustrates hypertensive disorders of pregnancy, especially preeclampsia, in both the basic and clinical aspects. Preeclampsia is a pregnancy-specific multi-organ disorder and a leading cause of maternal and neonatal mortality. The pathophysiology of pregnancy-specific disorders was long unknown, but recently many new findings have been reported from the point of view of pathophysiology. Furthermore, this complication of pregnancy, especially preeclampsia, is a potent risk factor for chronic conditions such as cardiovascular disease, diabetes mellitus, kidney disease, and hypertension. The book is composed of seven parts including genetic background, pathology, pathophysiology, and the latest prediction and treatment of preeclampsia. Specific basic topics such as immunological maladaptation, placental adenosine signaling, and new prediction markers are also expounded by experts. Thus it benefits not only obstetricians, pediatricians, nephrologists, diabetologists, and cardiologists, but also immunologists, endocrinologists, geneticists, pathologists, biologists, and molecular biologists who are interested in the treatment of hypertension in pregnancy.

Recurrent Pregnancy Loss

Posted onAuthorKieran Lamb

Author: Asher Bashiri, Avi Harlev, Ashok Agarwal Pages: 211 Size: 2.71 MB Format: PDF Publisher: Springer Verlag
Published: 01 January, 2016
eISBN-13: 9783319274522

Providing the latest evidence-based information on etiology, evaluation and treatment, this unique text provides an in-depth, comprehensive discussion of the epidemiology, genetic and endocrinologic factors and medical and surgical management of recurrent pregnancy loss (RPL). Taking a multidisciplinary approach including psychological treatment and patient perspectives, all aspects of current RPL prevention and treatment are elucidated. Detailed chapters provide real-world illustrative material and cover the set-up and management of RPL clinics and databases, containing practical tips. Recurrent Pregnancy Loss will be an excellent resource for OB-GYN specialists, general and reproductive endocrinologists, radiologists, hematologists, psychiatrists, psychologists, and any other investigators or clinicians treating patients confronted with this emotionally and physically trying condition.

Integrated approaches to infertility, IVF, and recurrent miscarriage

Posted onAuthorKieran Lamb

Author: Edited By Susan Bedford And Justine Bold. Pages: 378 Size: 3.29 MB Format: PDF Publisher: Singing Dragon
Published: 21 October, 2015
eISBN-13: 9780857012319

A comprehensive integrative handbook on fertility treatment, and Assisted Reproduction Techniques (ART), the book is written by specialist contributors for health professionals and Complementary and Alternative Medicine (CAM) practitioners, and for those seriously considering ART themselves. Integrated approaches to infertility offer both a greater awareness and understanding of the combination of factors that can influence the chances of success when undergoing different types of ART. Leading experts review the evidence and discuss the benefits of different approaches to support the physiological and emotional aspects of fertility and fertility treatment. The book covers everything from identifying and treating conditions that may reduce fertility, including immunological abnormalities and specific male and female factors, to how nutrition, acupuncture, reflexology and yoga can support couples going through assisted reproduction, including helping to improve some immunological aspects. There is also a chapter that looks specifically at support for the over 40’s.

Fundamentals of infection prevention and control

Posted onAuthorKieran Lamb

Author: Debbie Weston. Pages: 401 Size: 4.8 MB Format: PDF Publisher: Wiley-Blackwell
Published: 01 July, 2013
eISBN-13: 9781118307717

Reviews of first edition: This book tells every healthcare professional all they need to know about infection control A user-friendly, valuable source of knowledge on a subject that can be confusing and complicated. Nursing Standard A valuable contribution within any health or social environment.” Journal of Community Nursing Infection prevention and control is an essential component of nursing care, and a crucially important subject area for both nursing students and qualified nurses. Fundamentals of Infection Prevention and Control gives readers a firm grasp of the principles of infection control, how they relate to clinical practice and the key issues surrounding the subject. It provides a comprehensive guide to the prevention, management and control of healthcare associated infections, and the basic elements of microbiology, immunology and epidemiology that underpin them. Thoroughly revised in line with current policy, this new edition contains brand-new chapters on a range of topics including the role of the Infection Prevention and Control Team, audit and surveillance, and the management of outbreaks. Also incorporating a range of case studies and examples as well as additional online content, it is essential reading for all nursing students as well as qualified nursing and healthcare professionals. Explores both principles and practice of a crucial subject areaAccessible and user-friendly, with a range of features to help study including key definitions, links back to clinical practice, and chapter learning outcomes and summaries.

Oh’s Intensive Care Manual, 8th ed.

Posted onAuthorKieran Lamb

Author: Andrew D. Bersten , Jonathan Handy, T. E. Oh. Pages: 1,713 Size: 35.41 MB Format: PDF Publisher: Elsevier
Published: 15 August, 2018
eISBN-13: 9780702076060

For nearly 40 years, Oh’s Intensive Care Manual has been the quick reference of choice for ICU physicians at all levels of experience. The revised 8th edition maintains this tradition of excellence, providing fast access to practical information needed every day in today’s intensive care unit. This bestselling manual covers all aspects of intensive care in sufficient detail for daily practice while keeping you up to date with the latest innovations in the field.

  • New coverage of the latest developments in ICU imaging techniques, including ultrasound.
  • New information on the latest advances in ECMO (Extracorporeal Membrane Oxygenation) for cardiac and respiratory failure, ARDS, septic shock, neurologic disorders, muscle function, and hemodynamic therapy.
  • New co-editor Dr. Jonathan Handy shares his knowledge and expertise on acid-base disturbances during critical illness, critical care transfers, intravenous fluid therapy, cardiovascular physiology, burn management, sepsis, and the immunological impact of surgery and burn injury.

Best of Five MCQs for the Acute Medicine SCE

Posted onAuthorKieran Lamb

Author: Edited By Nigel Lane, Louise Powter, Samir Patel. Pages: 455 Size: 7.67 MB Format: PDF Publisher: Oxford University Press
Published: 17 March, 2016
eISBN-13: 9780191669682

Best of Five MCQs for the Acute Medicine SCE is a new revision resource designed specifically for this high-stakes exam. Containing over 350 Best of Five multiple choice questions, this dedicated guide will help candidates to prepare successfully. The content mirrors the SCE in Acute Medicine Blueprint to ensure candidates are fully prepared for all the topics that may appear in the exam. Topics range from how to manage acute problems in cardiology or neurology to managing acute conditions such as poisoning. All answers have full explanations and further reading to ensure high quality self-assessment and quick recognition of areas that require further study.

Oxford Textbook of Medicine

Posted onAuthorKieran Lamb

Author: David A. Warrell, Timothy M. Cox, and John D. Firth
Format: Webpage Publisher: Oxford University Press
Published: 2010
Print ISBN-13: 9780199204854
DOI: 10.1093/med/9780199204854.001.1

The Oxford Textbook of Medicine is the foremost international textbook of medicine. Unrivalled in its coverage of the scientific aspects and clinical practice of internal medicine and its subspecialties, it is a fixture in the offices and wards of physicians around the world.

Oxford Handbook of General Practice (4 ed.)

Posted onAuthorKieran Lamb

Author: Chantal Simon, Hazel Everitt, Francoise van Dorp, and Matt Burkes
Format: Webpage Publisher: Oxford University Press
Published: 2014
Print ISBN-13: 9780199671038
DOI: 10.1093/med/9780199671038.001.0001

Fully revised to reflect the new changes to the GP contract and the GP curriculum, this fourth edition of the best-selling Oxford Handbook of General Practice is a practical guide to all aspects of general practice, including everything from vital clinical information to valuable practical guidance from experienced GPs. Comprehensively covering everything a doctor needs to work in, or manage a GP practice, this resource ensures readers are always up-to-date with the latest guidelines, the most recent protocols, and cutting-edge clinical information. It is fully illustrated, features many useful figures, diagrams, management boxes, and tables, and new full colour photographs have been added to the dermatology and ophthalmology chapters.

Oxford Handbook of Clinical Immunology and Allergy (3 ed.)

Posted onAuthorKieran Lamb

Author: Gavin Spickett
Format: Webpage Publisher: Oxford University Press
Published: 2013
Print ISBN-13: 9780199603244
DOI: 10.1093/med/9780199603244.001.0001

The Oxford Handbook of Clinical Immunology and Allergy is a unique, practical and clinically relevant guide for clinicians and laboratory staff to assist with the diagnosis and management of immunological/allergic disease, and the correct selection and interpretation of immunological tests, and has been expanded to include the latest developments, drugs, diagnostic tests, and therapy options in the field.

Oxford Handbook of Clinical and Laboratory Investigation (4 ed.)

Posted onAuthorKieran Lamb

Author: Drew Provan
Format: Webpage Publisher: Oxford University Press
Published: 2018
Print ISBN-13: 9780198766537

DOI: 10.1093/med/9780198766537.001.0001

nvestigation of patients with suspected disease has become highly complex, with an ever-expanding plethora of investigative techniques available to clinicians. This handbook details the techniques used in modern clinical medicine, across all the major specialties. Each chapter outlines the range of investigations available, along with preparation of the patient, complications, and interpretation of results. The handbook also includes a symptom-focused approach initially, which helps clinicians determine which system may be involved before, then reviews the specialty-specific sections of the book.

Oxford Textbook of Vasculitis (3 ed.)

Posted onAuthorKieran Lamb

Author: Gene V. Ball, Barri J. Fessler, and S. Louis Bridges, Jr.
Format: Webpage Publisher: Oxford University Press
Published: 2014
Print ISBN-13: 9780199659869
DOI: 10.1093/med/9780199659869.001.0001

The third edition of this definitive and highly-regarded reference resource provides a comprehensive review of vasculitis, a fascinating array of life-threatening and minor conditions caused by inflammatory syndromes and diseases that affect the blood vessels. This resource uniquely brings together concepts from both the biological and clinical aspects of vasculitis. Research in clinical immunology now invigorates the entire area of vasculitis and shapes a rational approach to pathogenesis, diagnosis, and treatment, which is the substance of this text. Over 40 chapters cover known vasculitic conditions, and are illustrated with over 250 full-colour photographs of clinical and pathologic findings, diagrams, and tables. Separate sections are devoted to basic science, clinical manifestations commonly seen in vasculitis, imaging and percutaneous interventions, individual diseases and syndromes, as well as conditions which can mimic vasculitis. Many of the conditions are rare, and it is the exceptional clinician who has much experience with more than a few of these; thus, the invaluable experience of the international team of authors makes this new edition truly indispensable.

Lecture Notes: Immunology

Posted onAuthorKieran Lamb

Author: Ian Todd, Gavin Spickett, Lucy Fairclough
Pages: 245 Size: 33.12 MB Format: PDF Publisher: Wiley-Blackwell
Published: 07 July, 2015
eISBN-13: 9781118451663

Immunology Lecture Notes provides a thorough grounding in basic concepts of immunity. Covering the core components of the immunology curriculum at medical school, it presents a concise overview of the immune system, its interactions with pathogens, the major areas of immunopathology, including immunodeficiency, allergy, autoimmunity, lymphoptopliferative diseases and transplantation, and their therapy. Immunology Lecture Notes includes: Full-colour descriptive illustrations and diagrams throughout, supplemented by new molecular graphics and anatomical scans New clinical cases developed as themes throughout the book to illustrate the practical application of immunological principles Fully updated self-assessment questions with expanded explanation of answers With learning objectives and key points guiding you through the vital concepts, Immunology Lecture Notes will help you to address the key disorders of the immune system, and use immunological developments in clinical practice.

Crash Course Haematology and Immunology

Posted onAuthorKieran Lamb

Author: Yousef Gargani.
Pages: 193 Size: 3.31 MB Format: PDF Publisher: Elsevier Health Science
Published: 23 April, 2015
eISBN-13: 9780723438922

The (printed) `Updated Edition` now comes with added value access to the complete, downloadable eBook version via Student Consult. Search, read and revise whilst on the move and use the interactive self-assessment to test your understanding. Crash Course – a more flexible, practical learning package than ever before. Crash Course – your effective every day study companion PLUS the perfect antidote for exam stress! Save time and be assured you have all the information you need in one place to excel on your course and achieve exam success. A winning formula now for over 15 years, each series volume has been fine tuned and fully updated, with an improved layout tailored to make your life easier. Especially written by senior medical students or recent graduates – those who have just been in the exam situation – with all information thoroughly checked and quality assured by expert faculty advisers, the result are books which exactly meet your needs and you know you can trust. Commencing with `Learning Objectives`, every chapter guides you succinctly through the topic, giving full coverage of the curriculum whilst avoiding unnecessary and often confusing detail. A fully revised self-assessment section matching the latest exam formats is also included. This volume presents two of the fastest moving medical disciplines, immunology and haematology, where molecular discoveries rapidly translate into new diagnostic tests and treatments in everyday medicine. This book clearly relates the important underlying principles in these areas with the latest clinical applications.

Fast Facts: Diagnosing Cutaneous T-cell Lymphoma

Posted onAuthorKieran Lamb

Paul L Haun; Julia Scarisbrick, Julia

Pages: 86 Size: 51.72 MB Format: EPUB Publisher: Health Press
Published: 22 August, 2016
eISBN-13: 9781910797297

Cutaneous T-cell lymphoma (CTCL) is one of the great mimickers . To be certain of the diagnosis, there must be clear correlation between the pathological and clinical findings, making collaboration between clinicians and pathologists essential. Knowing the patient’s history, lesion description and diagnostic work-up will help the pathologist make a more informed decision with respect to the histopathology under the microscope. Likewise, understanding the terminology used in the pathology report will improve the clarity of the clinician s diagnosis.

Fast Facts: Diagnosing Cutaneous T-Cell Lymphoma is designed to help primary care providers, dermatologists and pathologists speak the same language. With over 100 superb clinical and pathological images, this concise, practical handbook will ensure clear communication with respect to the clinical presentation, histopathology and immunophenotyping of:

  • early and advanced mycosis fungoides and its variants
  • Sézary syndrome
  • other non-mycosis fungoides CTCLs.

Handbook of Lung Cancer and Other Thoracic Malignancies

Posted onAuthorKieran Lamb

Gregory P. Kalemkerian, Jessica S. Donington, Elizabeth M. Gore, Suresh S. Ramalingam.

Pages: 284 Size: 15.28 MB Format: EPUB Publisher: Demos Medical Publishing
Published: 28 November, 2016
eISBN-13: 9781617052729

A practical guide to management of lung cancer and other cancers of the thoracic cavity. Edited by a multidisciplinary team of cancer specialists from leading institutions, the book is an essential day-to-day reference for evidence-based care in thoracic oncology.

This state-of-the-art handbook focuses on evidence-based conventional and novel treatment strategies that have been transforming the landscape of lung cancer and related tumors. It includes guidance on video-assisted thoracoscopic surgery, adjuvant chemotherapy, combined-modality therapy, molecular diagnostic testing leading to molecularly targeted therapy, immunotherapy, stereotactic radiotherapy, and site-directed treatment of oligometastatic disease.

Practical and applicable to the care of real-life patients, this pocket-style resource covers the entirety of the field and is indispensable for clinical oncologists treating and managing thoracic cancer as well as trainees in medical, radiation, and surgical oncology programs needing an accessible point of care resource in one of the most dynamic subspecialty areas in oncology.

Immuno-Oncology

Posted onAuthorKieran Lamb

Edited By Olivier Michielin, George Coukos.

Pages: 129 Size: 3.96 MB Format: EPUB Publisher: Karger
Published: 09 September, 2015
eISBN-13: 9783318055900

Over the last decade, immuno-oncology has witnessed an astonishing pace of discovery and innovation translating into unprecedented successes in the clinical setting, arguably representing one of the most profound and transforming revolution in the history of cancer therapy. This book provides a concise and accurate outline of the main developments in major tumor types including melanoma, lung, breast, brain and renal cell cancers. In addition, transversal chapters that describe the commonalities of some of the therapeutic strategies are provided to cover topics like immune checkpoint biology, T cell engineering or rational combination therapies. Each chapter has been authored by senior key opinion leaders in their respective fields to provide the most up-to-date view on cancer immuno-oncology. To reflect on the key translational aspect of immuno-oncology, all chapters are making explicit connections between basic science discoveries and the resulting translational therapeutic strategies. Immuno-Oncology will be an invaluable source of information for scientists interested in the translation of basic immunology into the clinical practice, as well as for clinician interested in deepening their knowledge of current and upcoming immune strategies in the fight against cancers.